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<p class=MsoPlainText><span style='color:blue'>/*<o:p></o:p></span></p>
<p class=MsoPlainText><span style='color:blue'>Script to add STN synaps
es (AMPA
synapses from subthalamic nucleus) to GP model. <o:p></o:p></span></p>
<p class=MsoPlainText><span style='color:blue'>The compartments that re
ceive
the inputs must be listed in an ascii text file.<o:p></o:p></span></p>
<p class=MsoPlainText><span style='color:blue'>*/<o:p></o:p></span></p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
<p class=MsoPlainText>str STNfilename = “stn_syns.asc”</p>
<p class=MsoPlainText>randseed 78923456 </p>
<p class=MsoPlainText>str stncompartment</p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
<p class=MsoPlainText><span style='color:blue'>//create input element t
ree
outside of the cell path<o:p></o:p></span></p>
<p class=MsoPlainText>if (!{exists /inputs})</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>create neutral
/inputs</p>
<p class=MsoPlainText>end</p>
<p class=MsoPlainText>create neutral /inputs/STN</p>
<p class=MsoPlainText>num_STN = 0</p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
<p class=MsoPlainText><span style='color:blue'>// Open the file with th
e list
of compartment names<o:p></o:p></span></p>
<p class=MsoPlainText><span style='color:blue'>// File MUST NOT have an
y blank
lines at the end, or function will fail.<o:p></o:p></span></p>
<p class=MsoPlainText>openfile {STNfilename} r</p>
<p class=MsoPlainText>stncompartment = {readfile {STNfilename}}</p>
<p class=MsoPlainText><span style='color:blue'>//cycle through STN inpu
t
compartments<o:p></o:p></span></p>
<p class=MsoPlainText>while (! {eof {STNfilename}})</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>num_STN =
{num_STN} + 1</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan><span
style='color:blue'>//Add AMPA synapse from library<o:p></o:p></span></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>copy
/library/AMPA {cellpath}/{stncompartment}/AMPA</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>addmsg<span
style="mso-spacerun: yes"> </span>{cellpath}/{stncompartment}/AMPA \</
p>
<p class=MsoPlainText><span style='mso-tab-count:2'>
</span>{cellpath}/{stncompartment}
CHANNEL Gk Ek</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>addmsg<span
style="mso-spacerun: yes"> </span>{cellpath}/{stncompartment} \</p>
<p class=MsoPlainText><span style='mso-tab-count:2'>
</span>{cellpath}/{stncompartment}/AMPA
VOLTAGE Vm</p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan><span
style='color:blue'>//set up timetable<o:p></o:p></span></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>create neutral
/inputs/STN/{stncompartment}</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>create
timetable /inputs/STN/{stncompartment}/timetable</p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>if ({STN_rate}
> 0)</p>
<p class=MsoPlainText><span style='mso-tab-count:2'>
</span>setfield
/inputs/STN/{stncompartment}/timetable<span style='mso-tab-count:2'>
</span>\</p>
<p class=MsoPlainText><span style='mso-tab-count:3'>
</span>maxtime
{rundur} act_val 1.0 method 2 <span style='mso-tab-count:2'>
</span>\</p>
<p class=MsoPlainText><span style='mso-tab-count:3'>
</span>meth_desc1
{1/{STN_rate}} meth_desc2 0.005 meth_desc3 3<span style='mso-tab-count:1'
> </span></p>
<p class=MsoPlainText><span style='mso-tab-count:2'>
</span>call
/inputs/STN/{stncompartment}/timetable TABFILL</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>end</p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan><span
style='color:blue'>//set up spikegen<o:p></o:p></span></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>create
spikegen /inputs/STN/{stncompartment}/spikegen</p>
<p class=MsoPlainText><span style="mso-spacerun: yes">
</span>setfield
/inputs/STN/{stncompartment}/spikegen <span style='mso-tab-count:3'>
</span>\</p>
<p class=MsoPlainText><span style='mso-tab-count:2'>
</span>output_amp
1 thresh 0.5</p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
<p class=MsoPlainText><span style='color:blue'><span style="mso-space
run:
yes"> </span>//connect timetables to AMPA synapses<o:p></o:p
></span></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>if ({STN_rate}
> 0)</p>
<p class=MsoPlainText><span style="mso-spacerun: yes">
</span><span
style='mso-tab-count:1'> </span>addmsg /inputs/STN/{stncompartme
nt}/timetable
\</p>
<p class=MsoPlainText><span style="mso-spacerun: yes">
</span><span
style='mso-tab-count:2'> </span>/inputs/STN/{s
tncompartment}/spikegen
INPUT activation</p>
<p class=MsoPlainText><span style="mso-spacerun: yes">
</span><span
style='mso-tab-count:1'> </span>addmsg /inputs/STN/{stncompartme
nt}/spikegen
\</p>
<p class=MsoPlainText><span style="mso-spacerun: yes">
</span><span
style='mso-tab-count:2'> </span>{cellpath}/{st
ncompartment}/AMPA SPIKE</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>end</p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan><span
style='color:blue'>// get next compartment name<o:p></o:p></span></p>
<p class=MsoPlainText><span style='mso-tab-count:1'> </s
pan>stncompartment
= {readfile {STNfilename}}</p>
<p class=MsoPlainText>end</p>
<p class=MsoPlainText>closefile {STNfilename}</p>
<p class=MsoPlainText><![if !supportEmptyParas]> <![endif]><o:p></o:
p></p>
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